Organisation | Principal Investigator | Bank activity | Key publications

.:: Organisation


Department of Neurology
Ziemssenstr. 1a
80336 Munich


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.:: Principal Investigator

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Dr. Peter Schneiderat

Phone: +49 - 89/5160-7400
Fax: +49 - 89 5160 7402

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.:: Bank activity

The Muscle Tissue Culture Collection (MTCC) is located at the Friedrich-Baur-Institute at the University of Munich. The Friedrich-Baur-Institute is part of the Department of Neurology, with a strong focus on neuromuscular diseases, research and patient care.

The MTCC biobank collects, processes, stores and distributes myoblasts of a wide range of neuromuscular disease entities. Projects focussing on functional experiments studying the pathogenic mechanism of neuromuscular disorders or the cellular application of molecular therapies in the muscle cell, benefit from this service. MTCC was founded in 1998 and is a service structure of the German Muscular Dystrophy Network MD-NET and founding partner of EuroBioBank. More than 3500 muscle samples have been collected, cultivated, analyzed and archived since.

MTCC regular training sessions to individuals interested in techniques using primary muscle cell cultures on demand. Topics include the extraction of satellite cells from myoblasts, the establishment of primary myoblast cultures, cryoconservation and immortalization. For more information, please contact


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.:: Key publications

  • Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A research. Yoon S, Stadler G, Beermann ML, Schmidt EV, Windelborn JA, Schneiderat P, Wright WE, Miller JB. Skelet Muscle. 2013 Dec 6;3(1):28. [Epub ahead of print]

  • Flow cytometry for the analysis of a-dystroglycan glycosylation in fibroblasts from patients with dystroglycanopathies. Stevens E, Torelli S, Feng L, Phadke R, Walter MC, Schneiderat P, Eddaoudi A, Sewry CA, Muntoni F. PLoS One. 2013 Jul 22;8(7):e68958. doi: 10.1371/journal.pone.0068958. Print 2013.

  • miR-411 is up-regulated in FSHD myoblasts and suppresses myogenic factors. Harafuji N, Schneiderat P, Walter MC, Chen YW. Orphanet J Rare Dis. 2013 Apr 5;8:55. doi: 10.1186/1750-1172-8-55.

  • Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.Tedesco FS, Gerli MF, Perani L, Benedetti S, Ungaro F, Cassano M, Antonini S, Tagliafico E, Artusi V, Longa E, Tonlorenzi R, Ragazzi M, Calderazzi G, Hoshiya H, Cappellari O, Mora M, Schoser B, Schneiderat P, Oshimura M, Bottinelli R, Sampaolesi M, Torrente Y, Broccoli V, Cossu G. Sci Transl Med. 2012 Jun 27;4(140):140ra89. doi: 10.1126/scitranslmed.3003541.

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